When some bad blood with old foes compromises their ideal Thanksgiving, the gang decides to make amends by breaking bread with those they've hurt.
After creative differences over what constitutes tasteful nudity cause Frank to pull his money out of "Lethal Weapon 6" during filming, Mac, Dennis, and Charlie screen their rough footage for investors in hopes of raising enough capital to finish the production of their latest masterpiece.
When an experiment successfully multiplies Charlie's intellect and takes him away from the bar, the rest of the gang find themselves struggling to complete the menial "Charlie Work" that has kept the bar running for so long.
When a severe flu outbreak sweeps through Philadelphia, the gang chooses to voluntarily quarantine themselves inside of Paddy's in an attempt to keep their singing voices pristine for an upcoming singing competition.
When a routine trip to a convenience store places the gang in the middle of an armed robbery, each of them is forced to explore how they react in extreme situations.
Everyone in the gang gets a day to do what they want while everyone else in the gang must participate willingly. This is Mac's Day... and its got twice the "Mac".
The gang does their best to recoup their investments in questionable schemes by dumping their losses on Ben the soldier while trying to avoid being duped again by whatever mastermind is pulling their strings.
Tired of failing to be recognized for their years of service in the bar industry, the gang changes their ways to give the patrons what they think they want.
After Frank appears on Local Television advocating gun ownership, the rest of the gang takes a look at the ownership process and alternatives to find a common ground on this still heated issue.
Dee starts to embrace the desperate, self-loathing qualities the guys have beaten into her over the years, sending her stand-up comedy career to unexpected places.