Sam and Dean hit the road to help an old friend, but it appears that their luck may have finally run out and they are the ones who may be in need of rescue.
Sam and Eileen are faced with the brutal truth. Meanwhile Dean and Cass work together in the hopes of getting a step ahead of Chuck.
Sam, Dean and Castiel’s continued search for a way to defeat Chuck leads them to unexpected places and toward unlikely allies.
Dean goes off on his own to take on a case. Meanwhile, Castiel has an idea of how he can help Sam track down God.
Sam and Dean are visited by an old friend. Castiel investigates the disappearance of a local teen.
Sam and Dean’s routine case turns out to be anything but.
Sam and Dean investigate the mysterious death of a girl and the disappearance of another.
Sam and Dean together with Rowena work tirelessly to keep all of hell from breaking loose. Castiel cannot forgive an arrogant betrayal.
Sam, Dean and Castiel call on Rowena to help keep the evil souls at bay and get an unexpected assist from Ketch.
Picking up here we left off last season, Sam, Dean and Castiel are left to defend the world after all the souls in hell have been released and are back on Earth and free to kill again.