Original name: A.P. Bio
When Harvard philosophy scholar Jack Griffin finds himself teaching high school in Toledo, Ohio, he tosses the syllabus and recruits his students to help enact revenge on his rival.
Jack finds out his ex-girlfriend Meredith needs a venue for a charity fundraiser and has the perfect place: his student Victor's house. Victor and the other kids are inspired by Jack to party for the first time.
Jack receives an offer from Miles' publisher to write a book of feel-good philosophy that could be his ticket out of Toledo. Durbin accidentally sets off an emotional firestorm when he reveals that while Stef chose Mary as her emergency contact, Mary chose Michelle.
When Jack is attracted to a student's mother at a parent-teacher conference, he feigns interest in her son; a group of parents complain to principal Durbin when they notice a piece of controversial student art from Mary's class.
Jack reluctantly agrees to go out on the town with Mary, Stef, and Michelle; his superiority complex proves difficult for the women to overcome; principal Durbin feels threatened when Helen fills in for him on the school's morning announcements.
When Jack gets into a petty dispute with the student council president, the situation escalates much too far; Stef sells makeup at school as a side business.
While Principal Durbin struggles with budget cuts, Jack discovers his students pity him - so he rallies, making a splash at the school bake sale and getting kicked out of the bookstore for life.
When Jack leaves his class unattended, a student injury sets off an official investigation and lands Jack in "teacher jail." An aggressive teacher's union rep sets her sights on Principal Durbin. The students' excitement for a substitute teacher are dashed when they find out it's Helen.
Jack Griffin loses out on his dream job and becomes a high school teacher of Advanced Placement biology in his hometown of Toledo, Ohio.